Could someone please explain to me what the following means about a liver cancer patient?

Published on Sep 11th, 2010 under All.By admin

[Epithelial Cancer related Question]

I have an 80 year old man whose FNA tests say that he has Adenocarcinoma, Malignant Epithelial cells whose features suggest glandular formation. An abdominal scan had sad said intraabdominal malignancy with hepatic metastases. He was given expensive medication such as Xeloda. His legs are very swollen, why?
I do not understand what all this means. Could someone please explain to me and tell me how long I should give him till death. The doctor said the site of origin is not known. How long can he live?what does all this medical vocabulary mean?please

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3 Comments

sotos_poulman  on September 11th, 2010

Adenocarcinoma: Cancer formation on the patient’s glances

Malignant Epithelial cells whose features suggest glandular formation: means the epithelial cells (which are cells that help protect our organs by producing substances to kill the “invaders”) have been changed in a way that shows the doctors there is cancer

intraabdominal malignancy with hepatic metastases: the cancer started in the abdominal area and now goes (“metastases”) to the liver (“hepar” in greek)

swollen legs: due to the liver’s malfunction (caused by the cancer that has now been transfered there too)

no one can tell for sure how long the patient can live, depends on many factors. for sure there is not much time, since the cancer symptoms are so evident. i would say less than 6 months, but not for sure.

good luck
xxx

Belliger  on September 11th, 2010

Hello,

I’m sorry about this.

My translation is: There is a cancer (“carcinoma”) which originated in some glandular (“adeno-”) tissue, somewhere within the abdomen. It has spread secondarily (“metastasized”) to the liver, (“hepatic”).

There may be some obstruction by the bulk of the cancer, to lymph fluid return from the legs; or alternatively, he may haver a disturbance of his blood proteins, which is causing the legs to remain swollen.

The cancer cannot be removed surgically because (a) there is no diagnosed primary tumour to be removed, and (b) it has spread to the liver and you can’t remove that.

It’s difficult to know how long he is going to live. He is likely to lose weight and waste away; he may get jaundice from the loss of proper liver function; he may get a bowel obstruction from spread of the cancer within the abdomen; the cancer may spread to somewhere else dangerous, like the brain; he may get so weak that he gets a serious infection like pneumonia.

From this distance I would hesitate to guess. His doctor should be in a better position than me. If you pressed me, maybe several months, or more if he responds well to the treatment.

I hope this is of some help.

Best wishes,

Belliger (retired uk gp)

blueman20032500  on September 11th, 2010

Classification of cancer determines appropriate treatment and helps determine the prognosis. Cancer develops progressively from an alteration in a cell’s genetic structure due to mutations, to cells with uncontrolled growth patterns. Classification is made according to the site of origin, histology (or cell analysis; called grading), and the extent of the disease (called staging).
Site of Origin
Adenocarcinoma – originates in glandular tissue
Grading

Grading involves examining tumor cells that have been obtained through biopsy under a microscope. The abnormality of the cells determines the grade of the cancer. Increasing abnormality increases the grade, from 1 – 4. Cells that are well differentiated closely resemble mature, specialized cells. Cells that are undifferentiated are highly abnormal, that is, immature and primitive
Staging
Staging is the classification of the extent of the disease. There are several types of staging methods. The tumor, node, metastases (TNM) system classifies cancer by tumor size (T), the degree of regional spread or node involvement (N), and distant metastasis (M
Chemotherapy may cause short term (acute), long term (chronic), and permanent side effects, some of which may be severe. In many cases, side effects of chemotherapy can be prevented or controlled
The pancreas is an organ of the digestive system. It is located near the stomach and small intestine and has two major jobs or functions. The exocrine pancreas makes enzymes that help in the digestion of food products, and the endocrine pancreas produces several hormones that have diverse functions. Cancers of the pancreas can occur in the exocrine pancreas (classic pancreatic adenocarcinomas
Prognosis

Despite the many recent advances in cancer treatment , pancreatic cancer remains difficult to treat. There are several reasons for this, including tumor-related issues (i.e., low chemotherapy sensitivity, early metastasis, and low likelihood of resection at time of presentation) and treatment-related issues (i.e., limited effective chemotherapy drugs, non-optimal use of available treatments, severe side effects, and poor rate of participation in clinical trials).

he is end stage adnocarinoma with hepatic failure and cant use chemotherapy cause hepatic affection and prognosis is bad ,i guess few monthes sorry

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